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Western blot analysis in NCI-H460 cell line lysates (35ug/lane).
Western blot analysis in NCI-H460 cell line lysates (35ug/lane).

GTPBP3 Antibody

CATALOG NUMBER: 60-598

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This GTPBP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 293-320 amino acids from the Central region of human GTPBP3.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
52 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
GTPBP3
Additional Names:
tRNA modification GTPase GTPBP3, mitochondrial, GTP-binding protein 3, Mitochondrial GTP-binding protein 1, GTPBP3, MTGP1
Protein Accession Number:
Q969Y2
Protein Gi Number:
313104112
Ncbi Gene Id Number:
84705
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This locus encodes a GTP-binding protein. The encodedprotein is localized to the mitochondria and may play a role inmitochondrial tRNA modification. Polymorphisms at this locus may beassociated with severity of aminoglycoside-induced deafness, adisease associated with a mutation in the 12S rRNA. Alternativelyspliced transcript variants encoding different isoforms have beendescribed.
Background Reference 1:
Reiling, E., et al. Eur. J. Hum. Genet. 17(8):1056-1062(2009)
Background Reference 2:
Villarroya, M., et al. Mol. Cell. Biol. 28(24):7514-7531(2008)
Background Reference 3:
Bykhovskaya, Y., et al. Mol. Genet. Metab. 83(3):199-206(2004)
Background Reference 4:
Li, X., et al. Biochem. Biophys. Res. Commun. 312(3):747-754(2003)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-598

List Size:
400 ul

List Price:

$495.00

Datasheet
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