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Western blot analysis of anti-GUCY1B3 Pab(AP8171b) in Y79 cell line lysate.
Western blot analysis of anti-GUCY1B3 Pab(AP8171b) in Y79 cell line lysate.

Guanylyl Cyclase beta 1 Antibody

CATALOG NUMBER: 63-445

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This GUCY1B3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected between 589-619 amino acids of human GUCY1B3.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
71 kDa
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
GUCY1B3
Additional Names:
Guanylate cyclase soluble subunit beta-1, GCS-beta-1, Guanylate cyclase soluble subunit beta-3, GCS-beta-3, Soluble guanylate cyclase small subunit, GUCY1B3, GUC1B3, GUCSB3, GUCY1B1
Protein Accession Number:
Q02153
Protein Gi Number:
399328
Ncbi Gene Id Number:
2983
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Soluble guanylate cyclase (sGC), a heterodimeric protein consisting of an alpha and a beta subunit, catalyzes the conversion of GTP to the second messenger cGMP and functions as the main receptor for nitric oxide and nitrovasodilator drugs.
Background Reference 1:
Russwurm, M., et al., J. Biol. Chem. 276(48):44647-44652 (2001).
Background Reference 2:
Lucas, K.A., et al., Pharmacol. Rev. 52(3):375-414 (2000).
Background Reference 3:
Papapetropoulos, A., et al., J. Cell. Physiol. 167(2):213-221 (1996).
Background Reference 4:
Giuili, G., et al., Hum. Genet. 91(3):257-260 (1993).

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

63-445

List Size:
400 ul

List Price:

$495.00

Datasheet
Shipping Info

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