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Western blot analysis in MDA-MB231 cell line lysates (35ug/lane).
Western blot analysis in MDA-MB231 cell line lysates (35ug/lane).

GUCA2B Antibody

CATALOG NUMBER: 58-458

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This GUCA2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 69-97 amino acids from the C-terminal region of human GUCA2B.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
12 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
GUCA2B
Additional Names:
Guanylate cyclase activator 2B, Guanylate cyclase C-activating peptide 2, Guanylate cyclase C-activating peptide II, GCAP-II, Uroguanylin, UGN, GUCA2B
Protein Accession Number:
Q16661
Protein Gi Number:
2495130
Ncbi Gene Id Number:
2981
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Uroguanylin and guanylin (GUCA2A; MIM 139392), peptidehomologs of the bacterial heat-stable enterotoxins (e.g., the E.coli ST toxin; STa), are endogenous activators of the guanylatecyclase-2C receptor (GUCY2C; MIM 601330), which synthesizes cyclicGMP (cGMP), a key component of several intracellular signaltransduction pathways.
Background Reference 1:
Yoshikawa, Y., et al. Hypertens. Res. 30(9):789-796(2007)
Background Reference 2:
Guo, H.F., et al. Zhonghua Xin Xue Guan Bing Za Zhi 35(3):233-236(2007)
Background Reference 3:
Sindic, A., et al. Kidney Int. 67(4):1420-1427(2005)
Background Reference 4:
Maake, C., et al. Histochem. Cell Biol. 119(1):69-76(2003)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-458

List Size:
400 ul

List Price:

$495.00

Datasheet
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