GUCY2F Antibody

CATALOG NUMBER: 58-840

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
Immunogen:
This GUCY2F antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 828-856 amino acids from the C-terminal region of human GUCY2F.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
125 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
GUCY2F
Additional Names:
Retinal guanylyl cyclase 2, RETGC-2, Guanylate cyclase 2F, retinal, Guanylate cyclase F, GC-F, Rod outer segment membrane guanylate cyclase 2, ROS-GC2, GUCY2F, GUC2F, RETGC2
Protein Accession Number:
P51841
Protein Gi Number:
311033391
Ncbi Gene Id Number:
2986
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is a guanylyl cyclasefound predominantly in photoreceptors in the retina. The encodedprotein is thought to be involved in resynthesis of cGMP afterlight activation of the visual signal transduction cascade,allowing a return to the dark state. This protein is a single-passtype I membrane protein. Defects in this gene may be a cause ofX-linked retinitis pigmentosa.
Background Reference 1:
Blackford, A., et al. Cancer Res. 69(8):3681-3688(2009)
Background Reference 2:
Helten, A., et al. J. Neurochem. 103(4):1439-1446(2007)
Background Reference 3:
Wood, L.D., et al. Hum. Mutat. 27(10):1060-1061(2006)
Background Reference 4:
Ross, M.T., et al. Nature 434(7031):325-337(2005)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-840

List Size:
400 ul

List Price:

$495.00

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