H2AFZ Antibody

CATALOG NUMBER: 55-724

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, C. Elegans, Chicken, Zebrafish, Drosophila, Mouse, Rabbit, Xenopus, Rat
Immunogen:
This H2AFZ antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 59-86 amino acids from the C-terminal region of human H2AFZ.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight:
14 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
H2AFZ
Additional Names:
Histone H2AZ, H2A/z, H2AFZ, H2AZ
Protein Accession Number:
P0C0S5
Protein Gi Number:
83288408
Ncbi Gene Id Number:
3015
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Histones are basic nuclear proteins that are responsiblefor the nucleosome structure of the chromosomal fiber ineukaryotes. Nucleosomes consist of approximately 146 bp of DNAwrapped around a histone octamer composed of pairs of each of thefour core histones (H2A, H2B, H3, and H4). The chromatin fiber isfurther compacted through the interaction of a linker histone, H1,with the DNA between the nucleosomes to form higher order chromatinstructures. This gene encodes a replication-independent member ofthe histone H2A family that is distinct from other members of thefamily. Studies in mice have shown that this particular histone isrequired for embryonic development and indicate that lack offunctional histone H2A leads to embryonic lethality. [provided byRefSeq].
Background Reference 1:
Marques, M., et al. Epigenetics 5(4):267-272(2010)
Background Reference 2:
Svotelis, A., et al. Cell Cycle 9(2):364-370(2010)
Background Reference 3:
Thakar, A., et al. Biochemistry 48(46):10852-10857(2009)
Background Reference 4:
Hardy, S., et al. PLoS Genet.(10), E1000687 (2009) :

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

55-724

List Size:
400 ul

List Price:

$495.00

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