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Western blot analysis of HBG1 using rabbit polyclonal HBG1 Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the HBG1 gene.
Western blot analysis in K562 cell line lysates (35ug/lane).
Western blot analysis of HBG1 using rabbit polyclonal HBG1 Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the HBG1 gene.

HBG1 Antibody

CATALOG NUMBER: 57-207

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This HBG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 56-85 amino acids from the Central region of human HBG1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
16 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
HBG1
Additional Names:
Hemoglobin subunit gamma-1, Gamma-1-globin, Hb F Agamma, Hemoglobin gamma-1 chain, Hemoglobin gamma-A chain, HBG1
Protein Accession Number:
P69891
Protein Gi Number:
56749860
Ncbi Gene Id Number:
3047
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The gamma globin genes (HBG1 and HBG2) are normallyexpressed in the fetal liver, spleen and bone marrow. Two gammachains together with two alpha chains constitute fetal hemoglobin(HbF) which is normally replaced by adult hemoglobin (HbA) atbirth. In some beta-thalassemias and related conditions, gammachain production continues into adulthood. The two types of gammachains differ at residue 136 where glycine is found in the G-gammaproduct (HBG2) and alanine is found in the A-gamma product (HBG1).The former is predominant at birth. The order of the genes in thebeta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta-- beta--3'.
Background Reference 1:
Zhou, D., et al. Nat. Genet. 42(9):742-744(2010)
Background Reference 2:
Miccio, A., et al. Mol. Cell. Biol. 30(14):3460-3470(2010)
Background Reference 3:
Nuinoon, M., et al. Hum. Genet. (2009) In press :
Background Reference 4:
da Cunha, A.F., et al. Hemoglobin 33(6):439-447(2009)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-207

List Size:
400 ul

List Price:

$495.00

Datasheet
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