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Western blot analysis of extracts from NIH-3T3 tissue using HDAC6 (Phospho-Ser22) Antibody. The lane on the right is treated with the antigen-specific peptide.
Western blot analysis of extracts from NIH-3T3 tissue using HDAC6 (Phospho-Ser22) Antibody. The lane on the right is treated with the antigen-specific peptide.

HDAC6 (phospho Ser22) Antibody

CATALOG NUMBER: 80-033

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Immunogen:
HDAC6 (phospho Ser22) antibody was raised against a peptide sequence around phosphorylation site of serine 22 (P-Q-S (p)-P-P) derived from Human HDAC6.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
Western Blot: 1:500~1:1000
Specificity:
The antibody detects endogenous level of HDAC6 only when phosphorylated at serine 22.
Predicted Molecular Weight:
131 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Isotype:
IgG
Physical State:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
HDAC6
Additional Names:
HD6, HDA6, Histone deacetylase 6, JM21,
Protein Accession Number:
NP_006035.2
Protein Gi Number:
13128864
Ncbi Gene Id Number:
10013
Background:
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes By similarity. Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin.
Background Reference 1:
Chen S, Owens GC, Makarenkova H, Edelman DB (2010)PLoS One 5, e10848.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

80-033

List Size:
0.1 mg

List Price:

$376.00

Datasheet
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