HEMGN Antibody

CATALOG NUMBER: 56-873

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This HEMGN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 420-449 amino acids from the C-terminal region of human HEMGN.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
55 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
HEMGN
Additional Names:
Hemogen, Erythroid differentiation-associated gene protein, EDAG-1, Hemopoietic gene protein, Negative differentiation regulator protein, HEMGN, EDAG, NDR
Protein Accession Number:
Q9BXL5
Protein Gi Number:
74752432
Ncbi Gene Id Number:
55363
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
HEMGN regulates the proliferation and differentiation of hematopoietic cells. Overexpression block the TPA-induced megakaryocytic differentiation in the K562 cell model. May also prevent cell apoptosis through the activation of the nuclear factor-kappa B (NF-kB).
Background Reference 1:
Ding, Y.L., et al. J. Cell. Biochem. 110(4):866-874(2010)
Background Reference 2:
Moreno, L.M., et al. Hum. Mol. Genet. 18(24):4879-4896(2009)
Background Reference 3:
Lowe, J.K., et al. PLoS Genet.(2), E1000365 (2009) :
Background Reference 4:
Li, C.Y., et al. Biochim. Biophys. Acta 1779(10):606-615(2008)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

56-873

List Size:
400 ul

List Price:

$495.00

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