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Western blot analysis in K562 cell line lysates (35ug/lane).
Western blot analysis in K562 cell line lysates (35ug/lane).

HERC3 Antibody

CATALOG NUMBER: 60-595

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This HERC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-77 amino acids from the N-terminal region of human HERC3.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
117 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
HERC3
Additional Names:
Probable E3 ubiquitin-protein ligase HERC3, 632-, HECT domain and RCC1-like domain-containing protein 3, HERC3, KIAA0032
Protein Accession Number:
Q15034
Protein Gi Number:
2495699
Ncbi Gene Id Number:
8916
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
HERC3 belongs to the HERC family of ubiquitin ligases, allof which contain a HECT domain and at least 1 RCC1 (MIM179710)-like domain (RLD). The 350-amino acid HECT domain ispredicted to catalyze the formation of a thioester with ubiquitinbefore transferring it to a substrate, and the RLD is predicted toact as a guanine nucleotide exchange factor for small G proteins(Hochrainer et al., 2005 [PubMed 15676274]).
Background Reference 1:
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 2:
Hochrainer, K., et al. Genomics 85(2):153-164(2005)
Background Reference 3:
Cruz, C., et al. FEBS Lett. 488 (1-2), 74-80 (2001) :
Background Reference 4:
Cruz, C., et al. Cytogenet. Cell Genet. 87 (3-4), 263-264 (1999) :

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-595

List Size:
400 ul

List Price:

$495.00

Datasheet
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