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Western blot analysis in HepG2 cell line lysates (35ug/lane).
Western blot analysis in HepG2 cell line lysates (35ug/lane).

HERPUD1 Antibody

CATALOG NUMBER: 59-043

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This HERPUD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 55-83 amino acids from the N-terminal region of human HERPUD1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
44 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
HERPUD1
Additional Names:
Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein, Methyl methanesulfonate (MMF)-inducible fragment protein 1, HERPUD1, HERP, KIAA0025, MIF1
Protein Accession Number:
Q15011
Protein Gi Number:
3123034
Ncbi Gene Id Number:
9709
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The accumulation of unfolded proteins in the endoplasmicreticulum (ER) triggers the ER stress response. This responseincludes the inhibition of translation to prevent furtheraccumulation of unfolded proteins, the increased expression ofproteins involved in polypeptide folding, known as the unfoldedprotein response (UPR), and the destruction of misfolded proteinsby the ER-associated protein degradation (ERAD) system. This genemay play a role in both UPR and ERAD. Its expression is induced byUPR and it has an ER stress response element in its promoter regionwhile the encoded protein has an N-terminal ubiquitin-like domainwhich may interact with the ERAD system. This protein has beenshown to interact with presenilin proteins and to increase thelevel of amyloid-beta protein following its overexpression.Alternative splicing of this gene produces multiple transcriptvariants, some encoding different isoforms. The full-length natureof all transcript variants has not been determined. [provided byRefSeq].
Background Reference 1:
Hirabayashi, Y., et al. J. Immunol. 184(6):3276-3283(2010)
Background Reference 2:
McLaughlin, M., et al. J. Biol. Chem. 285(10):6960-6969(2010)
Background Reference 3:
Zabaneh, D., et al. PLoS ONE(8), E11961 (2010) :
Background Reference 4:
Ridker, P.M., et al. Circ Cardiovasc Genet 2(1):26-33(2009)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-043

List Size:
400 ul

List Price:

$495.00

Datasheet
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