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Western blot analysis of lysate from human brain tissue lysate, using Syncytin(ERVWE1) Antibody at 1:1000 at each lane.
Western blot analysis of lysate from human brain tissue lysate, using Syncytin(ERVWE1) Antibody at 1:1000 at each lane.

HERV Antibody

CATALOG NUMBER: 61-446

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This HERV (ERVWE1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 400-429 amino acids from the Central region of human HERV (ERVWE1).
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
60 kDa
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
ERVW-1
Additional Names:
Syncytin-1, Endogenous retrovirus group W member 1, Env-W, Envelope polyprotein gPr73, Enverin, HERV-7q Envelope protein, HERV-W envelope protein, HERV-W_7q212 provirus ancestral Env polyprotein, Syncytin, Surface protein, SU, gp50, Transmembrane protein, TM, gp24, ERVW-1, ERVWE1
Protein Accession Number:
Q9UQF0
Protein Gi Number:
47605755
Ncbi Gene Id Number:
30816
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. The protein, also known as syncytin, is expressed in the placental syncytiotrophoblast and is involved in fusion of the cytotrophoblast cells to form the syncytial layer of the placenta. This protein has the characteristics of a typical retroviral envelope protein, including a furin cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer.
Background Reference 1:
Oluwole,S.O., Amyotroph Lateral Scler(2), 67-72 (2007)
Background Reference 2:
Gong,R., Cell. Physiol. Biochem. 20 (5), 517-526 (2007)
Background Reference 3:
Antony,J.M., AIDS Res. Hum. Retroviruses 22 (12), 1253-1259 (2006)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

61-446

List Size:
200 ul

List Price:

$495.00

Datasheet
Shipping Info

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