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Western blot analysis in NCI-H460 cell line lysates (35ug/lane).
Western blot analysis in NCI-H460 cell line lysates (35ug/lane).

HERV-FRD Antibody

CATALOG NUMBER: 56-798

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Monkey
Immunogen:
This HERV-FRD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 79-107 amino acids from the N-terminal region of human HERV-FRD.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
60 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
ERVFRD-1
Additional Names:
Syncytin-2, Endogenous retrovirus group FRD member 1, Envelope polyprotein, HERV-FRD, HERV-FRD_6p241 provirus ancestral Env polyprotein, Surface protein, SU, Transmembrane protein, TM, ERVFRD-1, ERVFRDE1
Protein Accession Number:
P60508
Protein Gi Number:
44887864
Ncbi Gene Id Number:
405754
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Human endogenous retroviruses (HERVs) make upapproximately 8% of the human genome. Although most HERVs arenonfunctional, the HERV-W (ERVWE1; MIM 604659) and HERV-FRDenvelope (env) proteins can induce cell-cell fusion when expressedin cells possessing appropriate receptors (Blaise et al., 2003[PubMed 14557543]).
Background Reference 1:
Vargas, A., et al. J. Mol. Biol. 392(2):301-318(2009)
Background Reference 2:
Chen, C.P., et al. Biol. Reprod. 79(5):815-823(2008)
Background Reference 3:
Malassine, A., et al. Retrovirology 5,(2008) :
Background Reference 4:
Mangeney, M., et al. Proc. Natl. Acad. Sci. U.S.A. 104(51):20534-20539(2007)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

56-798

List Size:
400 ul

List Price:

$495.00

Datasheet
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