HIC1 Antibody

CATALOG NUMBER: 57-498

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Chicken, Mouse
Immunogen:
This HIC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 498-527 amino acids from the C-terminal region of human HIC1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
77 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
HIC1
Additional Names:
Hypermethylated in cancer 1 protein, Hic-1, Zinc finger and BTB domain-containing protein 29, HIC1, ZBTB29
Protein Accession Number:
Q14526
Protein Gi Number:
296439502
Ncbi Gene Id Number:
3090
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene functions as a growth regulatory and tumorrepressor gene. Hypermethylation or deletion of the region of thisgene have been associated with tumors and the contiguous-genesyndrome, Miller-Dieker syndrome. Alternative splicing of this generesults in multiple transcript variants.
Background Reference 1:
Pehlivan, S., et al. Cancer Genet. Cytogenet. 201(2):128-132(2010)
Background Reference 2:
Van Rechem, C., et al. Mol. Cell. Biol. 30(16):4045-4059(2010)
Background Reference 3:
Jugessur, A., et al. PLoS ONE(7), E11493 (2010) :
Background Reference 4:
Zhang, B., et al. Mol. Endocrinol. 23(12):2075-2085(2009)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-498

List Size:
400 ul

List Price:

$495.00

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