HIRIP3 Antibody

CATALOG NUMBER: 59-988

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This HIRIP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 287-316 amino acids from the Central region of human HIRIP3.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
62 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
HIRIP3
Additional Names:
HIRA-interacting protein 3, HIRIP3
Protein Accession Number:
Q9BW71
Protein Gi Number:
116242511
Ncbi Gene Id Number:
8479
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The HIRA protein shares sequence similarity with Hir1pand Hir2p, the two corepressors of histone gene transcriptioncharacterized in the yeast, Saccharomyces cerevisiae. Thestructural features of the HIRA protein suggest that it mayfunction as part of a multiprotein complex. Recently, severalcDNAs encoding HIRA-interacting proteins, or HIRIPs, have beenidentified. In vitro, the HIRIP3 gene product binds HIRA, as wellas H2B and H3 core histones, indicating that a complex containingHIRA-HIRIP3 could function in some aspects of chromatin and histonemetabolism.
Background Reference 1:
Kumar, R.A., et al. PLoS ONE(2), E4582 (2009) :
Background Reference 2:
Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
Background Reference 3:
Assrir, N., et al. Biol. Chem. 388(4):391-398(2007)
Background Reference 4:
Olsen, J.V., et al. Cell 127(3):635-648(2006)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-988

List Size:
400 ul

List Price:

$495.00

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