HIST2H2AC Antibody

CATALOG NUMBER: 60-780

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Rat, Bovine, Xenopus, Mouse, Chicken, Monkey, Zebrafish, D
Immunogen:
This HIST2H2AC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-46 amino acids from the Central region of human HIST2H2AC.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
14 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
HIST2H2AC
Additional Names:
Histone H2A type 2-C, Histone H2A-GL101, Histone H2A/q, HIST2H2AC, H2AFQ
Protein Accession Number:
Q16777
Protein Gi Number:
47117890
Ncbi Gene Id Number:
8338
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Histones are basic nuclear proteins that are responsiblefor the nucleosome structure of the chromosomal fiber ineukaryotes. Two molecules of each of the four core histones (H2A,H2B, H3, and H4) form an octamer, around which approximately 146 bpof DNA is wrapped in repeating units, called nucleosomes. Thelinker histone, H1, interacts with linker DNA between nucleosomesand functions in the compaction of chromatin into higher orderstructures. This gene is intronless and encodes a member of thehistone H2A family.
Background Reference 1:
Ishibashi, T., et al. Biochemistry 48(22):5007-5017(2009)
Background Reference 2:
Karaczyn, A.A., et al. Ann. Clin. Lab. Sci. 39(3):251-262(2009)
Background Reference 3:
Pinato, S., et al. BMC Mol. Biol. 10, 55 (2009) :
Background Reference 4:
Guerrero-Santoro, J., et al. Cancer Res. 68(13):5014-5022(2008)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-780

List Size:
400 ul

List Price:

$495.00

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