HIST2H2BF Antibody

CATALOG NUMBER: 58-399

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Bovine, Pr
Immunogen:
This HIST2H2BF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-42 amino acids from the N-terminal region of human HIST2H2BF.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
14 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
HIST2H2BF
Additional Names:
Histone H2B type 2-F, HIST2H2BF
Protein Accession Number:
Q5QNW6
Protein Gi Number:
74743113
Ncbi Gene Id Number:
440689
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Background Reference 1:
Kim, S.C., et al. Mol. Cell 23(4):607-618(2006)
Background Reference 2:
Pavri, R., et al. Cell 125(4):703-717(2006)
Background Reference 3:
Bonenfant, D., et al. Mol. Cell Proteomics 5(3):541-552(2006)
Background Reference 4:
Zhu, B., et al. Mol. Cell 20(4):601-611(2005)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-399

List Size:
400 ul

List Price:

$495.00

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