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Western blot analysis in Hela cell line lysates (35ug/lane).
Western blot analysis in Hela cell line lysates (35ug/lane).

HM13 Antibody

CATALOG NUMBER: 57-702

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This HM13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 325-354 amino acids from the C-terminal region of human HM13.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
41 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
HM13
Additional Names:
Minor histocompatibility antigen H13, 3423-, Intramembrane protease 1, IMP-1, IMPAS-1, hIMP1, Presenilin-like protein 3, Signal peptide peptidase, HM13, H13, IMP1, PSL3, SPP
Protein Accession Number:
Q8TCT9
Protein Gi Number:
25008563
Ncbi Gene Id Number:
81502
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene, which localizes to theendoplasmic reticulum, catalyzes intramembrane proteolysis of somesignal peptides after they have been cleaved from a preprotein.This activity is required to generate signal sequence-derived humanlymphocyte antigen-E epitopes that are recognized by the immunesystem, and to process hepatitis C virus core protein. The encodedprotein is an integral membrane protein with sequence motifscharacteristic of the presenilin-type aspartic proteases. Multipletranscript variants encoding several different isoforms have beenfound for this gene.
Background Reference 1:
Sato, T., et al. Biochemistry 45(28):8649-8656(2006)
Background Reference 2:
Loureiro, J., et al. Nature 441(7095):894-897(2006)
Background Reference 3:
Urny, J., et al. Biochim. Biophys. Acta 1759 (3-4), 159-165 (2006) :
Background Reference 4:
Friedmann, E., et al. J. Biol. Chem. 279(49):50790-50798(2004)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-702

List Size:
400 ul

List Price:

$495.00

Datasheet
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