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Western blot analysis in HL-60,K562,H-4-II-E cell line lysates (35ug/lane).
Western blot analysis in HL-60,K562,H-4-II-E cell line lysates (35ug/lane).

HMGB2 Antibody

CATALOG NUMBER: 62-718

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Pig, Rat
Immunogen:
This HMGB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 92-118 amino acids from the Central region of human HMGB2.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
24 kDa
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
HMGB2
Additional Names:
High mobility group protein B2, High mobility group protein 2, HMG-2, HMGB2, HMG2
Protein Accession Number:
P26583
Protein Gi Number:
123374
Ncbi Gene Id Number:
3148
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
HMGB2 is a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.
Background Reference 1:
Majumdar A., Brown D. 19:6643-6643(1991)
Background Reference 2:
Shirakawa H., Yoshida M.J.. 267:6641-6645(1992)
Background Reference 3:
Alexandre S., Li W.W.Nucleic Acids Res. 20:6413-6413(1992)
Background Reference 4:
Fan Z., Beresford P.J.Mol. Cell. Biol. 22:2810-2820(2002)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

62-718

List Size:
400 ul

List Price:

$495.00

Datasheet
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