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Western blot analysis in MDA-MB231 cell line lysates (35ug/lane).
Western blot analysis in MDA-MB231 cell line lysates (35ug/lane).

HNF1B Antibody

CATALOG NUMBER: 55-640

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This HNF1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 498-529 amino acids from the C-terminal region of human HNF1B.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
61 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
HNF1B
Additional Names:
Hepatocyte nuclear factor 1-beta, HNF-1-beta, HNF-1B, Homeoprotein LFB3, Transcription factor 2, TCF-2, Variant hepatic nuclear factor 1, vHNF1, HNF1B, TCF2
Protein Accession Number:
P35680
Protein Gi Number:
547664
Ncbi Gene Id Number:
6928
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a member of the homeodomain-containingsuperfamily of transcription factors. The protein binds to DNA aseither a homodimer, or a heterodimer with the related proteinhepatocyte nuclear factor 1-alpha. The gene has been shown tofunction in nephron development, and regulates development of theembryonic pancreas. Mutations in this gene result in renal cystsand diabetes syndrome and noninsulin-dependent diabetes mellitus,and expression of this gene is altered in some types of cancer.Multiple transcript variants encoding different isoforms have beenfound for this gene.
Background Reference 1:
Jablonski, K.A., et al. Diabetes 59(10):2672-2681(2010)
Background Reference 2:
Oram, R.A., et al. Am. J. Obstet. Gynecol. 203 (4), 364 (2010) :
Background Reference 3:
Takata, R., et al. Nat. Genet. 42(9):751-754(2010)
Background Reference 4:
Liu, H., et al. Prostate (2010) In press :

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

55-640

List Size:
400 ul

List Price:

$495.00

Datasheet
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