HNRNPC Antibody

CATALOG NUMBER: 55-373

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rabbit
Immunogen:
This HNRNPC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 279-306 amino acids from the C-terminal region of human HNRNPC.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For IHC-P starting dilution is: 1:50~100
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
34 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
HNRNPC
Additional Names:
Heterogeneous nuclear ribonucleoproteins C1/C2, hnRNP C1/C2, HNRNPC, HNRPC
Protein Accession Number:
P07910
Protein Gi Number:
108935845
Ncbi Gene Id Number:
3183
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene belongs to the subfamily of ubiquitouslyexpressed heterogeneous nuclear ribonucleoproteins (hnRNPs). ThehnRNPs are RNA binding proteins and they complex with heterogeneousnuclear RNA (hnRNA). These proteins are associated with pre-mRNAsin the nucleus and appear to influence pre-mRNA processing andother aspects of mRNA metabolism and transport. While all of thehnRNPs are present in the nucleus, some seem to shuttle between thenucleus and the cytoplasm. The hnRNP proteins have distinct nucleicacid binding properties. The protein encoded by this gene can actas a tetramer and is involved in the assembly of 40S hnRNPparticles. Multiple transcript variants encoding at least twodifferent isoforms have been described for this gene. [provided byRefSeq].
Background Reference 1:
Konig, J., et al. Nat. Struct. Mol. Biol. 17(7):909-915(2010)
Background Reference 2:
Lee, E.K., et al. Nat. Struct. Mol. Biol. 17(6):732-739(2010)
Background Reference 3:
Brunner, J.E., et al. Virology 400(2):240-247(2010)
Background Reference 4:
Ertel, K.J., et al. J. Virol. 84(9):4229-4242(2010)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

55-373

List Size:
400 ul

List Price:

$495.00

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