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Western blot analysis in U251 cell line lysates (35ug/lane).
HNRNPM Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human colon carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.
Western blot analysis in U251 cell line lysates (35ug/lane).

HNRNPM Antibody

CATALOG NUMBER: 57-415

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This HNRNPM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-50 amino acids from the N-terminal region of human HNRNPM.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight:
78 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
HNRNPM
Additional Names:
Heterogeneous nuclear ribonucleoprotein M, hnRNP M, HNRNPM, HNRPM, NAGR1
Protein Accession Number:
P52272
Protein Gi Number:
55977747
Ncbi Gene Id Number:
4670
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene belongs to the subfamily of ubiquitouslyexpressed heterogeneous nuclear ribonucleoproteins (hnRNPs). ThehnRNPs are RNA binding proteins and they complex with heterogeneousnuclear RNA (hnRNA). These proteins are associated with pre-mRNAsin the nucleus and appear to influence pre-mRNA processing andother aspects of mRNA metabolism and transport. While all of thehnRNPs are present in the nucleus, some seem to shuttle between thenucleus and the cytoplasm. The hnRNP proteins have distinct nucleicacid binding properties. The protein encoded by this gene has threerepeats of quasi-RRM domains that bind to RNAs. This protein alsoconstitutes a monomer of the N-acetylglucosamine-specific receptorwhich is postulated to trigger selective recycling of immatureGlcNAc-bearing thyroglobulin molecules. Multiple alternativelyspliced transcript variants are known for this gene but only twotranscripts has been isolated.
Background Reference 1:
Lleres, D., et al. EMBO Rep. 11(6):445-451(2010)
Background Reference 2:
Marko, M., et al. Exp. Cell Res. 316(3):390-400(2010)
Background Reference 3:
Russo, A., et al. Biochim. Biophys. Acta 1779(12):820-829(2008)
Background Reference 4:
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-415

List Size:
400 ul

List Price:

$495.00

Datasheet
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