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Western blot analysis in HL-60 cell line lysates (35ug/lane).
Western blot analysis in HL-60 cell line lysates (35ug/lane).

HOXB8 Antibody

CATALOG NUMBER: 58-305

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This HOXB8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 215-243 amino acids from the C-terminal region of human HOXB8.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
28 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
HOXB8
Additional Names:
Homeobox protein Hox-B8, Homeobox protein Hox-24, Homeobox protein Hox-2D, HOXB8, HOX2D
Protein Accession Number:
P17481
Protein Gi Number:
20141506
Ncbi Gene Id Number:
3218
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene is a member of the Antp homeobox family andencodes a nuclear protein with a homeobox DNA-binding domain. It isincluded in a cluster of homeobox B genes located on chromosome 17.The encoded protein functions as a sequence-specific transcriptionfactor that is involved in development. Increased expression ofthis gene is associated with colorectal cancer. Mice that have hadthe murine ortholog of this gene knocked out exhibit an excessivepathologic grooming behavior. This behavior is similar to thebehavior of humans suffering from the obsessive-compulsive spectrumdisorder trichotillomania.
Background Reference 1:
Kosaki, K., et al. Teratology 65(2):50-62(2002)
Background Reference 2:
Greer, J.M., et al. Neuron 33(1):23-34(2002)
Background Reference 3:
Knoepfler, P.S., et al. Oncogene 20(39):5440-5448(2001)
Background Reference 4:
Fujino, T., et al. Exp. Hematol. 29(7):856-863(2001)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-305

List Size:
400 ul

List Price:

$495.00

Datasheet
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