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Western blot analysis in mouse liver tissue lysates (35ug/lane).
Western blot analysis in zebra fish brain tissue lysates (35ug/lane).
Western blot analysis in mouse liver tissue lysates (35ug/lane).

HOXD10 Antibody

CATALOG NUMBER: 56-534

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Mouse, Zebrafish
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Mouse, Zebrafish
Homology:
Predicted species reactivity based on immunogen sequence: Chicken
Immunogen:
This HOXD10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 305-334 amino acids from the C-terminal region of human HOXD10.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
38 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
HOXD10
Additional Names:
Homeobox protein Hox-D10, Homeobox protein Hox-4D, Homeobox protein Hox-4E, HOXD10, HOX4D, HOX4E
Protein Accession Number:
P28358
Protein Gi Number:
143811403
Ncbi Gene Id Number:
3236
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene is a member of the Abd-B homeobox family andencodes a protein with a homeobox DNA-binding domain. It isincluded in a cluster of homeobox D genes located on chromosome 2.The encoded nuclear protein functions as a sequence-specifictranscription factor that is expressed in the developing limb budsand is involved in differentiation and limb development. Mutationsin this gene have been associated with Wilm's tumor and congenitalvertical talus (also known as 'rocker-bottom foot' deformity orcongenital convex pes valgus) and/or a foot deformity resemblingthat seen in Charcot-Marie-Tooth disease.
Background Reference 1:
Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009)
Background Reference 2:
Reddy, S.D., et al. Cancer Res. 68(20):8195-8200(2008)
Background Reference 3:
Gurnett, C.A., et al. Clin. Orthop. Relat. Res. 462, 27-31 (2007) :
Background Reference 4:
Zhao, X., et al. Am. J. Hum. Genet. 80(2):361-371(2007)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

56-534

List Size:
400 ul

List Price:

$495.00

Datasheet
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