HOXD11 Antibody

CATALOG NUMBER: 58-287

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This HOXD11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-216 amino acids from the Central region of human HOXD11.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
35 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
HOXD11
Additional Names:
Homeobox protein Hox-D11, Homeobox protein Hox-4F, HOXD11, HOX4F
Protein Accession Number:
P31277
Protein Gi Number:
223590220
Ncbi Gene Id Number:
3237
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene belongs to the homeobox family of genes. Thehomeobox genes encode a highly conserved family of transcriptionfactors that play an important role in morphogenesis in allmulticellular organisms. Mammals possess four similar homeobox geneclusters, HOXA, HOXB, HOXC and HOXD, located on differentchromosomes, consisting of 9 to 11 genes arranged in tandem. Thisgene is one of several homeobox HOXD genes located in a cluster onchromosome 2. Deletions that remove the entire HOXD gene cluster orthe 5' end of this cluster have been associated with severe limband genital abnormalities. The product of the mouse Hoxd11 geneplays a role in forelimb morphogenesis.
Background Reference 1:
Sugie, Y., et al. Brain Dev. 32(5):356-361(2010)
Background Reference 2:
Woo, C.J., et al. Cell 140(1):99-110(2010)
Background Reference 3:
Ester, A.R., et al. Am. J. Med. Genet.149A (12), 2745-2752 (2009) :
Background Reference 4:
Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-287

List Size:
400 ul

List Price:

$495.00

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