HOXD4 Antibody

CATALOG NUMBER: 58-503

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Chicken, Mouse
Immunogen:
This HOXD4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 195-223 amino acids from the C-terminal region of human HOXD4.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
28 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
HOXD4
Additional Names:
Homeobox protein Hox-D4, Homeobox protein HHOC13, Homeobox protein Hox-4B, Homeobox protein Hox-51, HOXD4, HOX4B
Protein Accession Number:
P09016
Protein Gi Number:
20141491
Ncbi Gene Id Number:
3233
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene belongs to the homeobox family of genes. Thehomeobox genes encode a highly conserved family of transcriptionfactors that play an important role in morphogenesis in allmulticellular organisms. Mammals possess four similar homeobox geneclusters, HOXA, HOXB, HOXC and HOXD, located on differentchromosomes, consisting of 9 to 11 genes arranged in tandem. Thisgene is one of several homeobox HOXD genes located at 2q31-2q37chromosome regions. Deletions that removed the entire HOXD genecluster or 5' end of this cluster have been associated with severelimb and genital abnormalities. The protein encoded by this genemay play a role in determining positional values in developing limbbuds. Alternatively spliced variants have been described but theirfull length nature has not been determined.
Background Reference 1:
Zhang, H., et al. Acta Pharmacol. Sin. 31(8):977-983(2010)
Background Reference 2:
Ester, A.R., et al. Am. J. Med. Genet.149A (12), 2745-2752 (2009) :
Background Reference 3:
Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009)
Background Reference 4:
Tan, Y., et al. BMC Mol. Biol. 10, 12 (2009) :

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-503

List Size:
400 ul

List Price:

$495.00

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