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Western blot analysis of extracts from K562 cells treated with forskolin using HP1γ (Phospho-Ser93) Antibody. The lane on the right is treated with the antigen-specific peptide.
Western blot analysis of extracts from K562 cells treated with forskolin using HP1γ (Phospho-Ser93) Antibody. The lane on the right is treated with the antigen-specific peptide.

HP1γ (phospho Ser93) Antibody

CATALOG NUMBER: 79-879

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
HP1γ (phospho Ser93) antibody was raised against a peptide sequence around phosphorylation site of Serine 93 (R-L-S (p)-L-S) derived from Human HP1γ .
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
Western Blot: 1:500~1:1000
Specificity:
The antibody detects endogenous levels of HP1γ only when phosphorylated at serine 93.
Predicted Molecular Weight:
24 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Isotype:
IgG
Physical State:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
CBX3
Additional Names:
HECH, HP1 gamma, HP1Hs-gamma, chromobox 3
Protein Accession Number:
NP_009207.2
Protein Gi Number:
15082258
Ncbi Gene Id Number:
11335;653972
Background:
At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.
Background Reference 1:
Ye Q., J. Biol. Chem. 271:14653-14656(1996).
Background Reference 2:
Ye Q., Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases.
Background Reference 3:
Koike N., FEBS Lett. 467:17-21(2000)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-879

List Size:
0.1 mg

List Price:

$376.00

Datasheet
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