HPS3 Antibody

CATALOG NUMBER: 58-778

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This HPS3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 262-290 amino acids from the N-terminal region of human HPS3.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
114 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
HPS3
Additional Names:
Hermansky-Pudlak syndrome 3 protein, HPS3
Protein Accession Number:
Q969F9
Protein Gi Number:
20532121
Ncbi Gene Id Number:
84343
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a protein containing a potentialclathrin-binding motif, consensus dileucine signals, andtyrosine-based sorting signals for targeting to vesicles oflysosomal lineage. The encoded protein may play a role in organellebiogenesis associated with melanosomes, platelet dense granules,and lysosomes. Mutations in this gene are associated withHermansky-Pudlak syndrome type 3. Alternate splice variants exist,but their full length sequence has not been determined. [providedby RefSeq].
Background Reference 1:
Torres-Serrant, M., et al. J. Pediatr. Hematol. Oncol. 32(6):448-453(2010)
Background Reference 2:
Huizing, M., et al. Platelets 18(2):150-157(2007)
Background Reference 3:
Santiago Borrero, P.J., et al. J. Invest. Dermatol. 126(1):85-90(2006)
Background Reference 4:
Boissy, R.E., et al. Am. J. Pathol. 166(1):231-240(2005)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-778

List Size:
400 ul

List Price:

$495.00

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