HRH4 Antibody

CATALOG NUMBER: 58-895

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This HRH4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 228-256 amino acids from the Central region of human HRH4.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
44 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
HRH4
Additional Names:
Histamine H4 receptor, H4R, HH4R, AXOR35, G-protein coupled receptor 105, GPRv53, Pfi-013, SP9144, HRH4, GPCR105
Protein Accession Number:
Q9H3N8
Protein Gi Number:
14194819
Ncbi Gene Id Number:
59340
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Histamine is a ubiquitous messenger molecule released frommast cells, enterochromaffin-like cells, and neurons. Its variousactions are mediated by a family of histamine receptors, which area subset of the G-protein coupled receptor superfamily. This geneencodes a histamine receptor that is predominantly expressed inhaematopoietic cells. The protein is thought to play a role ininflammation and allergy reponses. Multiple transcript variantsencoding different isoforms have been found for this gene.
Background Reference 1:
Yu, B., et al. Br. J. Dermatol. 163(5):935-940(2010)
Background Reference 2:
Gschwandtner, M., et al. Allergy 65(7):840-849(2010)
Background Reference 3:
Yu, B., et al. Br. J. Dermatol. 162(5):1038-1043(2010)
Background Reference 4:
Davila, S., et al. Genes Immun. 11(3):232-238(2010)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-895

List Size:
400 ul

List Price:

$495.00

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