HSC70 Interacting Protein HIP Antibody

CATALOG NUMBER: 62-195

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Immunogen:
This HSC70 Interacting Protein HIP (ST13) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-80 amino acids from human HSC70 Interacting Protein HIP (ST13).
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For IHC-P starting dilution is: 1:10~50
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
41 kDa
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
ST13
Additional Names:
Hsc70-interacting protein, Hip, Aging-associated protein 2, Progesterone receptor-associated p48 protein, Protein FAM10A1, Putative tumor suppressor ST13, Renal carcinoma antigen NY-REN-33, Suppression of tumorigenicity 13 protein, ST13, AAG2, FAM10A1, HIP, SNC6
Protein Accession Number:
P50502
Protein Gi Number:
6686278
Ncbi Gene Id Number:
6767
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
ST13 is an adaptor protein that mediates the association of the heat shock proteins HSP70 and HSP90. This protein has been shown to be involved in the assembly process of glucocorticoid receptor, which requires the assistance of multiple molecular chaperones. The expression of this protein is reported to be downregulated in colorectal carcinoma tissue suggesting that is a candidate tumor suppressor.
Background Reference 1:
Rajapandi, T., et al., J. Biol. Chem. 275(29):22597-22604 (2000).
Background Reference 2:
Morishima, Y., et al., J. Biol. Chem. 275(10):6894-6900 (2000).
Background Reference 3:
Chen, S., et al., J. Biol. Chem. 273(52):35194-35200 (1998).
Background Reference 4:
Johnson, B.D., et al., J. Biol. Chem. 273(6):3679-3686 (1998).

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

62-195

List Size:
400 ul

List Price:

$495.00

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