HSD11B2 Antibody

CATALOG NUMBER: 25-696

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HSD11B2.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
HSD11B2 antibody can be used for detection of HSD11B2 by ELISA at 1:62500. HSD11B2 antibody can be used for detection of HSD11B2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. XBL-10413 - Fetal Skeletal Muscle Tissue Lysate
Predicted Molecular Weight:
45 kDa
Purification:
Antibody is purified by peptide affinity chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store HSD11B2 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
HSD11B2
Additional Names:
HSD11B2, AME, AME1, HSD11K, HSD2, SDR9C3
Protein Accession Number:
NP_000187
Protein Gi Number:
119392083
Ncbi Gene Id Number:
3291
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
HSD11B2 catalyzes the conversion of cortisol to the inactive metabolite cortisone. It modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids.
Background Reference 1:
Hovanessian, A.G., (2008) Mol. Cell. Biol. 28 (11), 3830-3849.

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

25-696

List Size:
100 ul

List Price:

$519.00

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