Start Your Project

🛍️Explore our Promotions page to discover current deals, limited-time offers, and more!🌟

Western blot analysis in MCF-7,ZR-75-1,HepG2 cell line lysates (35ug/lane).
HSD17B4 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
Western blot analysis in MCF-7,ZR-75-1,HepG2 cell line lysates (35ug/lane).

HSD17B4 Antibody

CATALOG NUMBER: 56-474

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This HSD17B4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 341-370 amino acids from the Central region of human HSD17B4.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight:
80 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
HSD17B4
Additional Names:
Peroxisomal multifunctional enzyme type 2, MFE-2, 17-beta-hydroxysteroid dehydrogenase 4, 17-beta-HSD 4, D-bifunctional protein, DBP, Multifunctional protein 2, MPF-2, (3R)-hydroxyacyl-CoA dehydrogenase, 111n12, Enoyl-CoA hydratase 2, 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase, HSD17B4, EDH17B4
Protein Accession Number:
P51659
Protein Gi Number:
1706396
Ncbi Gene Id Number:
3295
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is a bifunctional enzymethat is involved in the peroxisomal beta-oxidation pathway forfatty acids. It also acts as a catalyst for the formation of3-ketoacyl-CoA intermediates from both straight-chain and2-methyl-branched-chain fatty acids. Defects in this gene thataffect the peroxisomal fatty acid beta-oxidation activity are acause of D-bifunctional protein deficiency (DBPD). An apparentpseudogene of this gene is present on chromosome 8. [provided byRefSeq].
Background Reference 1:
Canzian, F., et al. Hum. Mol. Genet. 19(19):3873-3884(2010)
Background Reference 2:
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Background Reference 3:
Kashiwayama, Y., et al. J. Biol. Chem. 285(34):26315-26325(2010)
Background Reference 4:
Pierce, S.B., et al. Am. J. Hum. Genet. 87(2):282-288(2010)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

56-474

List Size:
400 ul

List Price:

$495.00

Datasheet
Shipping Info

$65 Standard Overnight flat rate for as many products shipped within the United States.

$35 Dry Ice Shipment fee may be required on some items.

Note: Online orders only accepted for shipment within the USA. Click here for the list of international distributors.

Customize your order

Bulk Pricing Available

Custom Formulations: azide free, endotoxin testing & endotoxin removal.

Pair your antibody with a Lysate, Peptide, Control, & /OR Secondary Antibody.

Contact our Customer Care Team for more information

Custom Antibody Services

Speak to one of our custom antibody specialists to discuss your next custom antibody project.

New & Featured Products

HIV-1 p24 Antibody [9D2F6] (HRP)
HIV-1 p24 Antibody [9D2F6] (HRP)

CATALOG NUMBER: PM-7369-HRP

HIV-1 p24 Antibody [9D2F6] (biotin)
HIV-1 p24 Antibody [9D2F6] (biotin)

CATALOG NUMBER: PM-7369-biotin

HIV-1 p24 Antibody [9D2F6]
HIV-1 p24 Antibody [9D2F6]

CATALOG NUMBER: PM-7369