HSD17B6 Antibody

CATALOG NUMBER: 29-593

Clonality:
Polyclonal
Tested Applications:
ELISA, IHC, WB
Host Species:
Rabbit
Species Reactivity:
Dog, Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Dog, Human, Mouse
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HSD17B6.
Conjugate:
Unconjugated
Tested Applications:
ELISA, IHC, WB
Application Note:
HSD17B6 antibody can be used for detection of HSD17B6 by ELISA at 1:62500. HSD17B6 antibody can be used for detection of HSD17B6 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
A172 Cell Lysate
Predicted Molecular Weight:
35 kDa
Purification:
Antibody is purified by protein A chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store HSD17B6 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
HSD17B6
Additional Names:
HSD17B6, HSE, RODH, SDR9C6
Protein Accession Number:
NP_003716
Protein Gi Number:
19743808
Ncbi Gene Id Number:
8630
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
HSD17B6 has both oxidoreductase and epimerase activities and is involved in androgen catabolism. The oxidoreductase activity can convert 3 alpha-adiol to dihydrotestosterone, while the epimerase activity can convert androsterone to epi-androsterone. Both reactions use NAD+ as the preferred cofactor. HSD17B6 is a member of the retinol dehydrogenase family.The protein encoded by this gene has both oxidoreductase and epimerase activities and is involved in androgen catabolism. The oxidoreductase activity can convert 3 alpha-adiol to dihydrotestosterone, while the epimerase activity can convert androsterone to epi-androsterone. Both reactions use NAD+ as the preferred cofactor. This gene is a member of the retinol dehydrogenase family. Transcript variants utilizing alternative polyadenylation signals exist.
Background Reference 1:
Huang, X.F. (2001) Biochim. Biophys. Acta 1520 (2), 124-130.

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

29-593

List Size:
100 ul

List Price:

$473.00

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