HTR3A Antibody

CATALOG NUMBER: 31-116

Clonality:
Polyclonal
Tested Applications:
ELISA, IHC, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HTR3A.
Conjugate:
Unconjugated
Tested Applications:
ELISA, IHC, WB
Application Note:
HTR3A antibody can be used for detection of HTR3A by ELISA at 1:62500. HTR3A antibody can be used for detection of HTR3A by western blot at 1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. 1205 - Jurkat Cell Lysate
Predicted Molecular Weight:
55 kDa
Purification:
Antibody is purified by peptide affinity chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store HTR3A antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
HTR3A
Additional Names:
HTR3A, HTR3, 5HT3R, 5-HT-3, 5-HT3A, 5-HT3R
Protein Accession Number:
NP_000860
Protein Gi Number:
253735700
Ncbi Gene Id Number:
3359
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
HTR3A belongs to the ligand-gated ion channel receptor superfamily. It is the subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified.
Background Reference 1:
Panicker, S., et al., (2004) J. Biol. Chem. 279 (27), 28149-28158.

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

31-116

List Size:
100 ul

List Price:

$519.00

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