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Western blot analysis in MDA-MB453,K562 cell line lysates (35ug/lane).
Western blot analysis in MDA-MB453,K562 cell line lysates (35ug/lane).

HTR3A Antibody

CATALOG NUMBER: 56-271

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This HTR3A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-58 amino acids from the N-terminal region of human HTR3A.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
55 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
HTR3A
Additional Names:
5-hydroxytryptamine receptor 3A, 5-HT3-A, 5-HT3A, 5-hydroxytryptamine receptor 3, 5-HT-3, 5-HT3R, Serotonin receptor 3A, Serotonin-gated ion channel receptor, HTR3A, 5HT3R, HTR3
Protein Accession Number:
P46098
Protein Gi Number:
1168222
Ncbi Gene Id Number:
3359
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The product of this gene belongs to the ligand-gated ionchannel receptor superfamily. This gene encodes subunit A of thetype 3 receptor for 5-hydroxytryptamine (serotonin), a biogenichormone that functions as a neurotransmitter, a hormone, and amitogen. This receptor causes fast, depolarizing responses inneurons after activation. It appears that the heteromericcombination of A and B subunits is necessary to provide the fullfunctional features of this receptor, since either subunit aloneresults in receptors with very low conductance and responseamplitude. Alternatively spliced transcript variants encodingdifferent isoforms have been identified.
Background Reference 1:
Gatt, J.M., et al. Biol. Psychiatry 68(9):818-824(2010)
Background Reference 2:
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Background Reference 3:
Gatt, J.M., et al. Depress Anxiety 27(8):752-759(2010)
Background Reference 4:
Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

56-271

List Size:
400 ul

List Price:

$495.00

Datasheet
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