HTR7 Antibody

CATALOG NUMBER: 58-454

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This HTR7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 405-433 amino acids from the C-terminal region of human HTR7.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
54 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
HTR7
Additional Names:
5-hydroxytryptamine receptor 7, 5-HT-7, 5-HT7, 5-HT-X, Serotonin receptor 7, HTR7
Protein Accession Number:
P34969
Protein Gi Number:
8488960
Ncbi Gene Id Number:
3363
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The neurotransmitter, serotonin, is thought to play a rolein various cognitive and behavioral functions. The serotoninreceptor encoded by this gene belongs to the superfamily of Gprotein-coupled receptors and the gene is a candidate locus forinvolvement in autistic disorder and other neuropsychiatricdisorders. Three splice variants have been identified which encodeproteins that differ in the length of their carboxy terminal ends.
Background Reference 1:
Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010)
Background Reference 2:
Pinheiro, A.P., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :
Background Reference 3:
Corominas, R., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (1), 177-184 (2010) :
Background Reference 4:
Wei, Z., et al. Prog. Neuropsychopharmacol. Biol. Psychiatry 33(3):547-551(2009)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-454

List Size:
400 ul

List Price:

$495.00

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