HTRA4 Antibody

CATALOG NUMBER: 27-056

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HTRA4.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
HTRA4 antibody can be used for detection of HTRA4 by ELISA at 1:312500. HTRA4 antibody can be used for detection of HTRA4 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. XBL-10123 - Fetal Brain Tissue Lysate
Predicted Molecular Weight:
51 kDa
Purification:
Antibody is purified by peptide affinity chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store HTRA4 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
HTRA4
Additional Names:
HTRA4, FLJ90724,
Protein Accession Number:
NP_710159
Protein Gi Number:
24308541
Ncbi Gene Id Number:
203100
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
HTRA4 is a member of the HtrA family of proteases. The protein contains a putative signal peptide, an insulin growth factor binding domain, a Kazal protease inhibitor domain, a conserved trypsin domain and a PDZ domain. Based on studies on other related family members, this enzyme may function as a secreted oligomeric chaperone protease to degrade misfolded secretory proteins. Other human HtrA proteins have been implicated in arthritis, tumor suppression, unfolded stress response, apoptosis, and aging.
Background Reference 1:
Clausen, T., (2002) Mol. Cell 10 (3), 443-455.

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

27-056

List Size:
100 ul

List Price:

$499.00

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