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Recombinant Human CCL5/RANTES Protein was determined by SDS-PAGE under reducing conditions with Coomassie Blue.
Measured by its binding ability in a functional ELISA. Immobilized Human CCL5 (Catalog: 85-761) at 5 μg/mL (100 μL/well) can bind Mouse CXCL4 (Catalog: 86-049) with a linear range of 10-252.6 ng/mL.
Recombinant Human CCL5/RANTES Protein was determined by SDS-PAGE under reducing conditions with Coomassie Blue.

Human CCL5/RANTES Recombinant Protein (85-761)

CATALOG NUMBER: 85-761

Tested Applications:
Bioactivity Test, ELISA, Immunogen, SDS-PAGE, WB
Specifications
source-species:
E. coli
Species:
Human
source-species:
E. coli
Recombinant Protein Sequence:
Ser24-Ser91
Fusion Tag:
C-6His
Tested Applications:
Bioactivity Test, ELISA, Immunogen, SDS-PAGE, WB
Application Note:
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity Test
Predicted Molecular Weight:
8.69 kDa
Biological Activity:
Measured by its binding ability in a functional ELISA. Immobilized Human CCL5 at 5 μg/mL (100 μL/well) can bind Mouse CXCL4 with a linear range of 10-252.6 ng/mL.
Purity:
≥ 95 % as determined by SDS-PAGE.
Endotoxin:
< 1 EU/μg of the protein by LAL method.
physical-state:
Lyophilized
Buffer:
Supplied as a 0.22 μm filtered solution in PBS, pH 7.4.
Storage Conditions:
Store at -70°C. This product is stable at ≤ -70°C for up to 1 year from the date of receipt. For optimal storage, aliquot into smaller quantities after centrifugation and store at recommended temperature. Avoid repeated freeze-thaw cycles.
Additional Names:
SISd; eoCP; SCYA5; RANTES; TCP228; D17S136E; SIS-delta
Protein Accession Number:
NP_002976.2
Ncbi Gene Id Number:
6352
Background:
Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Alternative splicing results in multiple transcript variants that encode different isoforms.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

85-761

List Size:
0.01 mg, 0.05 mg

List Price:

Price range: $140.00 through $350.00

Datasheet
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