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Recombinant Human GDNFR-alpha-2/GFRA2 Protein was determined by SDS-PAGE under reducing conditions with Coomassie Blue.
Immobilized recombinant Human Neurturin at 5μg/mL (100μL/well) can bind recombinant Human GFRA2,the EC<sub>50</sub> of Human GFRA2 is 1.82μg/mL.
Recombinant Human GDNFR-alpha-2/GFRA2 Protein was determined by SDS-PAGE under reducing conditions with Coomassie Blue.

Human GDNFR-alpha-2/GFRA2 Recombinant Protein (84-981)

CATALOG NUMBER: 84-981

Tested Applications:
Bioactivity Test, ELISA, Immunogen, SDS-PAGE, WB
Specifications
source-species:
HEK293 cells
Species:
Human
source-species:
HEK293 cells
Recombinant Protein Sequence:
Ser22-Ser441
Fusion Tag:
C-His
Tested Applications:
Bioactivity Test, ELISA, Immunogen, SDS-PAGE, WB
Application Note:
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity Test
Predicted Molecular Weight:
47.59 kDa
Biological Activity:
Measured by its binding ability in a functional ELISA. Immobilized recombinant Human Neurturin at 5 μg/mL (100 μL/well) can bind recombinant Human GFRA2, the EC50 of Human GFRA2 is 1.82 μg/mL.
Purity:
≥ 95 % as determined by SDS-PAGE.
Endotoxin:
< 0.1 EU/μg of the protein by LAL method.
physical-state:
Lyophilized
Buffer:
Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.Contact us for customized product form or formulation.
Storage Conditions:
Store at -20°C.Store the lyophilized protein at -20°C to -80 °C up to 1 year from the date of receipt.
After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
Additional Names:
GFRA2,GDNFRB,NRTNR-ALPHA,NTNRA,RETL2,TRNR2
Protein Accession Number:
NP_001486.4
Ncbi Gene Id Number:
2675
Background:
Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. This gene is a candidate gene for RET-associated diseases.

FOR RESEARCH USE ONLY

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Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

84-981

List Size:
0.01 mg, 0.1 mg

List Price:

Price range: $84.00 through $280.00

Datasheet
Shipping Info

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