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Recombinant Human IgD Protein was determined by SDS-PAGE under reducing conditions with Coomassie Blue.
Recombinant Human IgD Protein was determined by SDS-PAGE under reducing conditions with Coomassie Blue.

Human IgD Recombinant Protein (86-083)

CATALOG NUMBER: 86-083

Tested Applications:
Bioactivity Test, ELISA, Immunogen, SDS-PAGE, WB
Specifications
Source Species:
HEK293 cells
Species:
Human
Source Species:
HEK293 cells
Recombinant Protein Sequence:
Arg99-Lys384
Fusion Tag:
C-His
Tested Applications:
Bioactivity Test, ELISA, Immunogen, SDS-PAGE, WB
Application Note:
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity Test
Predicted Molecular Weight:
31.89 kDa
Purity:
≥ 85% as determined by SDS-PAGE.
Endotoxin:
< 0.01 EU/μg of the protein by LAL method
Physical State:
Lyophilized
Buffer:
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Storage Conditions:
Store at -20°C.Store the lyophilized protein at -20°C to -80 °C up to 1 year from the date of receipt.
After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
Additional Names:
IGHD, IgD ,Ig delta chain C region,Ig delta chain C region NIG-65,Ig delta chain C region WAH ,Immunoglobulin heavy constant delta
Protein Accession Number:
P01880-1
Ncbi Gene Id Number:
3495
Background:
IgD is the major antigen receptor isotype on the surface of most peripheral B-cells, where it is coexpressed with IgM. The membrane-bound IgD (mIgD) induces the phosphorylation of CD79A and CD79B by the Src family of protein tyrosine kinases. Soluble IgD (sIgD) concentration in serum below those of IgG, IgA, and IgM but much higher than that of IgE. IgM and IgD molecules present on B cells have identical V regions and antigen-binding sites. After the antigen binds to the B-cell receptor, the secreted form sIgD is shut off. IgD is a potent inducer of TNF, IL1B, and IL1RN. IgD also induces release of IL6, IL10, and LIF from peripheral blood mononuclear cells. Monocytes seem to be the main producers of cytokines in vitro in the presence of IgD.

FOR RESEARCH USE ONLY

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Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

86-083

List Size:
0.1 mg

List Price:

$336.00

Datasheet
Shipping Info

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