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Recombinant Human IL-4R alpha/CD124 Protein was determined by SDS-PAGE under reducing conditions with Coomassie Blue.
Immobilized recombinant human IL4R at 2 μg/mL (100 μL/well) can bind recombinant human IL4. The ED<sub>50</sub> of recombinant human IL4R is 2-4 ng/mL.
Recombinant Human IL-4R alpha/CD124 Protein was determined by SDS-PAGE under reducing conditions with Coomassie Blue.

Human IL-4R alpha/CD124 Recombinant Protein (84-883)

CATALOG NUMBER: 84-883

Tested Applications:
Bioactivity Test, ELISA, Immunogen, SDS-PAGE, WB
Specifications
source-species:
HEK293 cells
Species:
Human
source-species:
HEK293 cells
Recombinant Protein Sequence:
Gly24-His232
Fusion Tag:
C-His
Tested Applications:
Bioactivity Test, ELISA, Immunogen, SDS-PAGE, WB
Application Note:
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity Test
Predicted Molecular Weight:
24.74 kDa
Biological Activity:
Measured by its binding ability in a functional ELISA. Immobilized recombinant human IL4R at 2 μg/mL (100 μL/well) can bind recombinant human IL4. The ED50 of recombinant human IL4R is 2-4 ng/mL.
Purity:
≥ 85 % as determined by SDS-PAGE.
Endotoxin:
< 0.1 EU/μg of the protein by LAL method.
physical-state:
Lyophilized
Buffer:
Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.Contact us for customized product form or formulation.
Storage Conditions:
Store at -20°C.Store the lyophilized protein at -20°C to -80 °C up to 1 year from the date of receipt.
After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
Additional Names:
IL4R,CD124,IL-4RA,IL4RA
Protein Accession Number:
NP_000409.1
Ncbi Gene Id Number:
3566
Background:
This protein is alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

84-883

List Size:
0.01 mg, 0.05 mg

List Price:

Price range: $140.00 through $350.00

Datasheet
Shipping Info

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