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Recombinant Human LGR5 / GPR49 protein was determined by SDS-PAGE under reducing conditions with Coomassie Blue.
Recombinant Human LGR5 / GPR49 protein was determined by SDS-PAGE under reducing conditions with Coomassie Blue.

Human LGR5 / GPR49 Recombinant Protein (85-123)

CATALOG NUMBER: 85-123

Tested Applications:
Bioactivity Test, ELISA, Immunogen, SDS-PAGE, WB
Specifications
Source Species:
HEK293 cells
Species:
Human
Source Species:
HEK293 cells
Recombinant Protein Sequence:
Gly 22 - Arg 561
Fusion Tag:
C-6His
Tested Applications:
Bioactivity Test, ELISA, Immunogen, SDS-PAGE, WB
Application Note:
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity Test
Predicted Molecular Weight:
60.38 kDa
Purity:
≥ 90 % as determined by SDS-PAGE.
Endotoxin:
< 0.01 EU/μg of the protein by LAL method
Physical State:
Lyophilized
Buffer:
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Storage Conditions:
Store at -20°C.Store the lyophilized protein at -20°C to -80 °C up to 1 year from the date of receipt.
After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
Additional Names:
LGR5, GPR49, GPR67,Leucine-rich repeat-containing G-protein coupled receptor 5
Protein Accession Number:
NM_003667.3
Ncbi Gene Id Number:
8549
Background:
LGR5 (also known as GPR49) is a seven-transmembrane protein of the class A Rhodopsin-like family of GPCRs. LGR5 and LGR4 bind the R-spondins with high affinity and mediate the potentiation of Wnt/β-catenin signaling by enhancing Wnt-induced LRP6 phosphorylation. The LGR5/RSPO complex could promote Wnt signalling via the neutralization of two transmembrane E3 ligases, RNF43 and ZNRF3.

FOR RESEARCH USE ONLY

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Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

85-123

List Size:
0.01 mg, 0.05 mg

List Price:

Price range: $140.00 through $315.00

Datasheet
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