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Recombinant Human MUC-16/CA125 Protein was determined by SDS-PAGE under reducing conditions with Coomassie Blue.
Immobilized Human MUC16(Catalog: 85-827) at 2 μg/mL (100 μL/well) can bind Human Mesothelin/MSLN (Catalog: 85-315) with a linear range of 0.5-23.7 ng/mL.
Recombinant Human MUC-16/CA125 Protein was determined by SDS-PAGE under reducing conditions with Coomassie Blue.

Human MUC-16/CA125 Recombinant Protein (85-827)

CATALOG NUMBER: 85-827

Tested Applications:
Bioactivity Test, ELISA, Immunogen, SDS-PAGE, WB
Specifications
source-species:
HEK293 cells
Species:
Human
source-species:
HEK293 cells
Recombinant Protein Sequence:
Gly12660-Met12923
Fusion Tag:
C-His
Tested Applications:
Bioactivity Test, ELISA, Immunogen, SDS-PAGE, WB
Application Note:
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity Test
Predicted Molecular Weight:
29.21 kDa
Biological Activity:
Measured by its binding ability in a functional ELISA. Immobilized Human MUC16 at 2 μg/mL (100 μL/well) can bind Human Mesothelin/MSLN with a linear range of 0.5-23.7 ng/mL.
Purity:
≥ 85% as determined by SDS-PAGE.
Endotoxin:
< 0.01 EU/μg of the protein by LAL method
physical-state:
Lyophilized
Buffer:
Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
Storage Conditions:
Store at -20°C.Store the lyophilized protein at -20°C to -80 °C up to 1 year from the date of receipt.
After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
Additional Names:
CA125,MUC16,mucin-16
Protein Accession Number:
NP_078966.2
Ncbi Gene Id Number:
94025
Background:
The CA125, also known as the MUC16, is a mucin protein that may be found in type I transmembrane or secreted forms that are used monitor the progress of epithelial ovarian cancer therapy. The CA 125 molecule is almost certainly a glycoprotein with a predominance of O-linkages. It is heterogeneous with regard to both size and charge, most likely due to continuous deglycosylation of side chains during its life-span in bodily fluids. It exists as a very large complex (perhaps as much as 4 million daltons) under natural conditions.

FOR RESEARCH USE ONLY

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Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

85-827

List Size:
0.01 mg, 0.05 mg

List Price:

Price range: $126.00 through $280.00

Datasheet
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