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Recombinant Human NKp30/NCR3/CD337 Protein was determined by SDS-PAGE under reducing conditions with Coomassie Blue.
The purity of Human NCR3/NKp300 Protein (Cat.84-961) was greater than 95% as determined by SEC-HPLC.
Immobilized recombinant Human B7-H6 at 2μg/mL (100 μL/well) can bind recombinant Human NCR3, the EC<sub>50</sub> of Human NCR3 is 66.43 ng/mL.
Recombinant Human NKp30/NCR3/CD337 Protein was determined by SDS-PAGE under reducing conditions with Coomassie Blue.

Human NKp30/NCR3/CD337 Recombinant Protein (84-961)

CATALOG NUMBER: 84-961

Tested Applications:
Bioactivity Test, ELISA, Immunogen, SDS-PAGE, WB
Specifications
source-species:
HEK293 cells
Species:
Human
source-species:
HEK293 cells
Recombinant Protein Sequence:
Leu19-Thr138
Fusion Tag:
C-hFc&His
Tested Applications:
Bioactivity Test, ELISA, Immunogen, SDS-PAGE, WB
Application Note:
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity Test
Predicted Molecular Weight:
39.86 kDa
Biological Activity:
Measured by its binding ability in a functional ELISA. Immobilized recombinant Human B7-H6 at 2 μg/mL (100 μL/well) can bind recombinant Human NCR3, the EC50 of Human NCR3 is 66.43 ng/mL.
Purity:
≥ 95 % as determined by SDS-PAGE;≥95 % as determined by HPLC.
Endotoxin:
< 0.1 EU/μg of the protein by LAL method.
physical-state:
Lyophilized
Buffer:
Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.Contact us for customized product form or formulation.
Storage Conditions:
Store at -20°C.Store the lyophilized protein at -20°C to -80 °C up to 1 year from the date of receipt.
After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
Additional Names:
NCR3,1C7,CD337,LY117,MALS,NKp30
Protein Accession Number:
NP_001138938.1
Ncbi Gene Id Number:
259197
Background:
Natural Cytotoxicity Triggering Receptor 3, NCR3, also known as NKp30, or CD337, is a natural cytotoxicity receptor. NKp30 is expressed on both resting and activated NK cells of the CD56dim, CD16+ subset that account for more that 85% of NK cells found in peripheral blood and spleen. NKp30 is absent from the CD56bright, CD16- subset that constitutes the majority of NK cells in lymph node and tonsil, however, its expression is up-regulated in these cells upon IL-2 activation .NKp30 is a member of the immunoglobulin superfamily and one of three existing natural cytotoxicity-triggering receptors. NKp30 is a glycosylated protein and is thought to be selectively expressed in resting and activated natural killer cells. NKp30 is a stimulatory receptor on human NK cells implicated in tumor immunity, and is capable of promoting or terminating dendritic cell maturation. NCR3 may play a role in inflammatory and infectious diseases.

FOR RESEARCH USE ONLY

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Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

84-961

List Size:
0.01 mg, 0.05 mg

List Price:

Price range: $126.00 through $280.00

Datasheet
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