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Recombinant Human PD-1/PDCD1/CD279 Protein was determined by SDS-PAGE under reducing conditions with Coomassie Blue.
The purity of Human PD-1 Protein (Cat.84-853) was greater than 90% as determined by SEC-HPLC.
Immobilized Recombinant Human PD-1 at 5 μg/mL (100uL/well) can bind Recombinant Human PD-L1 with a linear range of 0.5-2 μg/mL.
Recombinant Human PD-1/PDCD1/CD279 Protein was determined by SDS-PAGE under reducing conditions with Coomassie Blue.

Human PD-1/PDCD1/CD279 Recombinant Protein (84-853)

CATALOG NUMBER: 84-853

Tested Applications:
Bioactivity Test, ELISA, Immunogen, SDS-PAGE, WB
Specifications
source-species:
HEK293 cells
Species:
Human
source-species:
HEK293 cells
Recombinant Protein Sequence:
Leu25-Thr168
Fusion Tag:
C-His
Tested Applications:
Bioactivity Test, ELISA, Immunogen, SDS-PAGE, WB
Application Note:
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity Test
Predicted Molecular Weight:
16.89 kDa
Biological Activity:
Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human PD-1 at 5 μg/mL (100 μL/well) can bind Recombinant Human PD-L1 with a linear range of 0.5-2 μg/mL.
Purity:
≥ 95 % as determined by SDS-PAGE;≥ 90 % as determined by HPLC.
Endotoxin:
< 0.1 EU/μg of the protein by LAL method.
physical-state:
Lyophilized
Buffer:
Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.Contact us for customized product form or formulation.
Storage Conditions:
Store at -20°C.Store the lyophilized protein at -20°C to -80 °C up to 1 year from the date of receipt.
After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
Additional Names:
PDCD1, CD279, PD-1, PD1, SLEB2, hPD-1, hPD-l, hSLE1, programmed cell death 1,PD-1,CD279,PD1,SLEB2,hPD-1,hPD-l,hSLE1,PD-1/CD279
Protein Accession Number:
NP_005009.2
Ncbi Gene Id Number:
5133
Background:
This protein is a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

84-853

List Size:
0.01 mg, 0.05 mg

List Price:

Price range: $126.00 through $280.00

Datasheet
Shipping Info

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