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Recombinant Human PDGFR-beta/CD140b(E241D) Protein was determined by SDS-PAGE under reducing conditions with Coomassie Blue.
The purity of Human PDGFRB/CD140b Protein (Cat.84-910) was greater than 90% as determined by SEC-HPLC.
Immobilized recombinant Human PDGF-B at 2μg/mL (100 μL/well) can bind recombinant Human PDGFRB, the EC<sub>50</sub> of Human PDGFRB is 30.48 ng/mL.
Recombinant Human PDGFR-beta/CD140b(E241D) Protein was determined by SDS-PAGE under reducing conditions with Coomassie Blue.

Human PDGFR-beta/CD140b(E241D) Recombinant Protein (84-910)

CATALOG NUMBER: 84-910

Tested Applications:
Bioactivity Test, ELISA, Immunogen, SDS-PAGE, WB
Specifications
source-species:
HEK293 cells
Species:
Human
source-species:
HEK293 cells
Recombinant Protein Sequence:
Leu33-Phe530 (Glu241Asp)
Fusion Tag:
C-hFc&His
Tested Applications:
Bioactivity Test, ELISA, Immunogen, SDS-PAGE, WB
Application Note:
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity Test
Predicted Molecular Weight:
82.86 kDa
Biological Activity:
Measured by its binding ability in a functional ELISA. Immobilized recombinant Human PDGF-B at 2 μg/mL (100 μL/well) can bind recombinant Human PDGFRB. The EC50 of Human PDGFRB is 30.48 ng/mL.
Purity:
≥ 90% as determined by SDS-PAGE;≥ 90% as determined by HPLC.
Endotoxin:
< 0.1 EU/μg of the protein by LAL method.
physical-state:
Lyophilized
Buffer:
Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.Contact us for customized product form or formulation.
Storage Conditions:
Store at -20°C.Store the lyophilized protein at -20°C to -80 °C up to 1 year from the date of receipt.
After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
Additional Names:
CD140B,IBGC4,IMF1,JTK12,KOGS,PDGFR,PDGFR-1,PDGFR1,PENTT,PDGF Receptor beta,PDGFRB,PDGFR beta
Protein Accession Number:
NP_002600.1
Ncbi Gene Id Number:
5159
Background:
The protein is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.

FOR RESEARCH USE ONLY

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Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

84-910

List Size:
0.01 mg, 0.05 mg

List Price:

Price range: $112.00 through $252.00

Datasheet
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