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Recombinant Human Siglec-3/CD33 Protein was determined by SDS-PAGE under reducing (R) and non-reducing (NR) conditions.
Immobilized Human CD33 Protein at 1μg/mL (100 μL/well) can bind CD33 Rabbit pAb with a linear range of 0.03-1.66 ng/mL.
Recombinant Human Siglec-3/CD33 Protein was determined by SDS-PAGE under reducing (R) and non-reducing (NR) conditions.

Human Siglec-3/CD33 Recombinant Protein (84-943)

CATALOG NUMBER: 84-943

Tested Applications:
Bioactivity Test, ELISA, Immunogen, SDS-PAGE, WB
Specifications
source-species:
HEK293 cells
Species:
Human
source-species:
HEK293 cells
Recombinant Protein Sequence:
Asp18-His259
Fusion Tag:
C-hFc&His
Tested Applications:
Bioactivity Test, ELISA, Immunogen, SDS-PAGE, WB
Application Note:
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity Test
Predicted Molecular Weight:
53.63 kDa
Biological Activity:
Measured by its binding ability in a functional ELISA. Immobilized Human CD33 Protein at 1μg/mL (100 μL/well) can bind CD33 Rabbit pAb with a linear range of 0.03-1.66 ng/mL.
Purity:
≥ 95 % as determined by SDS-PAGE.
Endotoxin:
< 0.1 EU/μg of the protein by LAL method.
physical-state:
Lyophilized
Buffer:
Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.Contact us for customized product form or formulation.
Storage Conditions:
Store at -20°C.Store the lyophilized protein at -20°C to -80 °C up to 1 year from the date of receipt.
After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
Additional Names:
CD33, SIGLEC-3, SIGLEC3, p67, CD33 molecule,SIGLEC-3,SIGLEC3,p67
Protein Accession Number:
NP_001763.3
Ncbi Gene Id Number:
945
Background:
Myeloid cell surface antigen CD33 also known as Sialic acid binding Ig-like lectin 3, CD33 antigen or Siglec-3, is a member of the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. This Single-pass type I membrane protein contains 1 Ig-like C2-type (immunoglobulin-like) domain and 1 Ig-like V-type (immunoglobulin-like) domain. CD33/Siglec-3 induces apoptosis in acute myeloid leukemia (in vitro). CD33/Siglec-3 can function as a sialic acid-dependent cell adhesion molecule and that binding can be modulated by endogenous sialoglycoconjugates when CD33 is expressed in a plasma membrane.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

84-943

List Size:
0.01 mg, 0.05 mg

List Price:

Price range: $126.00 through $280.00

Datasheet
Shipping Info

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