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Recombinant Human TNFRSF17/BCMA/CD269 Protein was determined by SDS-PAGE under reducing conditions with Coomassie Blue.
Immobilized recombinant human BAFF at 5 μg/mL (100 μL/well) can bind recombinant human TNFRSF17 with a linear range of 3-20 ng/mL.
Loaded Human TNFRSF17/BCMA/CD269 Protein, C-hFc&His (Catalog: 84-939) on ProA Biosensor, can bind Human TNFSF13B/BAFF/CD257 Protein, no Tag (Catalog: 84-813) with an affinity constant of 2.62 nM as determined in BLI assay (Gator).
Recombinant Human TNFRSF17/BCMA/CD269 Protein was determined by SDS-PAGE under reducing conditions with Coomassie Blue.

Human TNFRSF17/BCMA/CD269 Recombinant Protein (84-939)

CATALOG NUMBER: 84-939

Tested Applications:
Bioactivity Test, ELISA, Immunogen, SDS-PAGE, WB
Specifications
source-species:
HEK293 cells
Species:
Human
source-species:
HEK293 cells
Recombinant Protein Sequence:
Met1-Ala54
Fusion Tag:
C-hFc&His
Tested Applications:
Bioactivity Test, ELISA, Immunogen, SDS-PAGE, WB
Application Note:
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity Test
Predicted Molecular Weight:
32.69 kDa
Biological Activity:
1.Measured by its binding ability in a functional ELISA. Immobilized recombinant human BAFF at 5 μg/mL (100 μL/well) can bind recombinant human TNFRSF17 with a linear range of 3-20 ng/mL.
2.Loaded Human TNFRSF17/BCMA/CD269 Protein, C-hFc&His on ProA Biosensor, can bind Human TNFSF13B/BAFF/CD257 Protein, no Tag with an affinity constant of 2.62 nM as determined in BLI assay (Gator).
Purity:
≥ 90 % as determined by SDS-PAGE.
Endotoxin:
< 0.1 EU/μg of the protein by LAL method.
physical-state:
Lyophilized
Buffer:
Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.Contact us for customized product form or formulation.
Storage Conditions:
Store at -20°C.Store the lyophilized protein at -20°C to -80 °C up to 1 year from the date of receipt.
After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
Additional Names:
TNFRSF17,BCM,BCMA,CD269,TNFRSF13A
Protein Accession Number:
NP_001183.2
Ncbi Gene Id Number:
608
Background:
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

84-939

List Size:
0.02 mg, 0.05 mg

List Price:

Price range: $196.00 through $315.00

Datasheet
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