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Recombinant Human UBE2L3 Protein was determined by SDS-PAGE under reducing conditions with Coomassie Blue.
Recombinant Human UBE2L3 Protein was determined by SDS-PAGE under reducing conditions with Coomassie Blue.

Human UBE2L3 Recombinant Protein (84-818)

CATALOG NUMBER: 84-818

Tested Applications:
Bioactivity Test, ELISA, Immunogen, SDS-PAGE, WB
Specifications
source-species:
E. coli
Species:
Human
source-species:
E. coli
Recombinant Protein Sequence:
Met1-Asp154
Fusion Tag:
C-His
Tested Applications:
Bioactivity Test, ELISA, Immunogen, SDS-PAGE, WB
Application Note:
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity Test
Predicted Molecular Weight:
18.70 kDa
Purity:
≥ 95 % as determined by SDS-PAGE.
Endotoxin:
Please contact us for more information.
physical-state:
Lyophilized
Buffer:
Supplied in 50mM HEPES, 200mM NaCl, 10%glycerol, 1mM TCEP, pH 7.0Contact us for customized product form or formulation.
Storage Conditions:
Store at -70°C. This product is stable at ≤ -70°C for up to 1 year from the date of receipt. For optimal storage, aliquot into smaller quantities after centrifugation and store at recommended temperature. Avoid repeated freeze-thaw cycles.
Additional Names:
UBE2L3,E2-F1,L-UBC,UBCH7,UbcM4,Ube2L3 / UBCH7
Protein Accession Number:
NP_003338.1
Ncbi Gene Id Number:
7332
Background:
Ubiquitin-conjugating Enzyme E2L 3 (UBE2L3),also known as Ubiquitin-conjugating Enzyme H7 (UbcH7), is a member of the Ubiquitin-conjugating (E2) enzyme family (1). The human UbcH7 protein shares 100% amino acid (aa) sequence identity with the mouse and rat orthologs. UBE2L3 is catalytically active with HECT and RBR domain-containing families of Ubiquitin ligases (E3s). UBE2L3 localizes to both the nucleus and cytoplasm in human cells. UBE2L3 depletion results in an extended S phase and a reduced rate of proliferation, suggesting that it may play a role in the cell cycle. In humans, single nucleotide polymorphisms in UBE2L3 are associated with systemic lupus erythematosus and Crohn's disease, suggesting that UbcH7 is important for proper immune system function.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

84-818

List Size:
0.05 mg

List Price:

$280.00

Datasheet
Shipping Info

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