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HVEM Recombinant Protein

CATALOG NUMBER: 92-488

Specifications
Source Species:
HEK293 cells
Species:
Mouse
Source Species:
HEK293 cells
Recombinant Protein Sequence:
Gln39-Val207
Fusion Tag:
C-Fc tag
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Predicted Molecular Weight:
45.6 kD
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Physical State:
Lyophilized
Buffer:
Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Storage Conditions:
Lyophilized protein should be stored at -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at -20°C for 3 months.
Ncbi Official Symbol:
Tnfrsf14
Additional Names:
Protein Tnfrsf14, Herpesvirus entry mediator (HVEM), TR2 (TNF receptor-like molecule), ATAR (another TRAF-associated receptor), TNFRSF14, TR2, CD270
Protein Accession Number:
Q80WM9
Protein Gi Number:
291219911
Ncbi Gene Id Number:
230979
Background:
Mouse Protein Tnfrsf14, is a type I transmembrane protein belonging to the TNF receptor superfamily. It is tumor necrosis factor receptor superfamily member 14 and expressed on the surface of T cells during the resting state. Interaction of HVEM with TNF family member LIGHT co-stimulates T cells and promotes inflammation. HVEM also triggers inhibitory signaling cascade in effector T (Teff) cells and regulatory T cells (Tregs) as a ligand of B and T lymphocyte attenuator. Tnfrsf14 is detected in peripheral blood T cells, B cells, monocytes and in various tissues enriched in lymphoid cells. It has demonstrated that HVEM Ig is able to exert a significant antiviral effect against HSV-1 infection in vivo.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

92-488

List Size:
0.05 mg

List Price:

$275.00

Datasheet
Shipping Info

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