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Western blot analysis in NCI-H460 cell line lysates (35ug/lane).
Western blot analysis in NCI-H460 cell line lysates (35ug/lane).

ICA1 Antibody

CATALOG NUMBER: 58-732

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This ICA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 84-111 amino acids from the N-terminal region of human ICA1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
55 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
ICA1
Additional Names:
Islet cell autoantigen 1, 69 kDa islet cell autoantigen, ICA69, Islet cell autoantigen p69, ICAp69, p69, ICA1
Protein Accession Number:
Q05084
Protein Gi Number:
20141584
Ncbi Gene Id Number:
3382
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a protein with an arfaptin homologydomain that is found both in the cytosol and as membrane-bound formon the Golgi complex and immature secretory granules. This proteinis believed to be an autoantigen in insulin-dependent diabetesmellitus and primary Sjogren's syndrome. Alternatively splicedvariants which encode different protein isoforms have beendescribed; however, not all variants have been fully characterized.
Background Reference 1:
Jin, Y., et al. Nat. Genet. 42(7):576-578(2010)
Background Reference 2:
Rose, J. Phd, et al. Mol. Med. (2010) In press :
Background Reference 3:
Buffa, L., et al. Eur. J. Cell Biol. 87(4):197-209(2008)
Background Reference 4:
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-732

List Size:
400 ul

List Price:

$495.00

Datasheet
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